Strong growth momentum continues with excellent R&D pipeline delivery in the year-to-date
Revenue and EPS summary
| H1 2025 | % Change | Q2 2025 | % Change | |||
| $m | Actual | CER1 | $m | Actual | CER | |
| – Product Sales | 26,670 | 8 | 10 | 13,795 | 11 | 10 |
| – Alliance Revenue | 1,293 | 38 | 38 | 654 | 36 | 35 |
| Product Revenue2 | 27,963 | 9 | 11 | 14,449 | 12 | 11 |
| Collaboration Revenue | 82 | 68 | 66 | 8 | >2x | >2x |
| Total Revenue | 28,045 | 9 | 11 | 14,457 | 12 | 11 |
| Reported EPS ($) | 3.46 | 31 | 32 | 1.58 | 27 | 31 |
| Core3 EPS ($) | 4.66 | 16 | 17 | 2.17 | 10 | 12 |
Key performance elements for H1 2025
(Growth numbers at constant exchange rates)
* Total Revenue up 11% to $28,045m, driven by double-digit growth in Oncology and BioPharmaceuticals
* Growth in Total Revenue across all major geographic regions
* Core Operating profit increased 13%
* Core EPS increased 17% to $4.66
* 12 positive Phase III readouts and 19 approvals in major regions
* Interim dividend increased 3% to $1.03 (76.7 pence, 9.81 SEK)
Pascal Soriot, Chief Executive Officer, AstraZeneca, said:
“Our strong momentum in revenue growth continued through the first half of the year and the delivery from our broad and diverse pipeline has been excellent, with 12 positive key Phase III trial readouts including for baxdrostat, gefurulimab, and Tagrisso in just the past few weeks.
As we enter our next phase of growth, we have pledged $50 billion to continue to grow in the US, which includes the largest manufacturing investment in AstraZeneca’s history, set for Virginia. This landmark investment reflects not only America’s importance but also our confidence in our innovative medicines to transform global health and power AstraZeneca’s ambition to deliver $80 billion revenue by 2030.”
Guidance
AstraZeneca reiterates its Total Revenue and Core EPS guidance4 for FY 2025 at CER, based on the average foreign exchange rates through 2024.
Total Revenue is expected to increase by a high single-digit percentage
Core EPS is expected to increase by a low double-digit percentage
The Core Tax rate is expected to be between 18-22%
If foreign exchange rates for July 2025 to December 2025 were to remain at the average rates seen in June 2025, it is anticipated that FY 2025 Total Revenue growth and Core EPS growth would be broadly similar to the growth at CER (previously a low single-digit percentage adverse impact was anticipated)